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Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells

✍ Scribed by Towatari, M; Iida, H; Tanimoto, M; Iwata, H; Hamaguchi, M; Saito, H

Book ID
110053471
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
109 KB
Volume
11
Category
Article
ISSN
0887-6924

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## Abstract We studied the effect of prolonged activation of mitogen‐activated protein kinase (MAPK) signaling on 1,25 dihydroxyvitamin D (1,25(OH)~2~D~3~) action in the immortalized human prostate epithelial cell line RWPE1 and its Ki‐Ras transformed clone RWPE2. 1,25(OH)~2~D~3~‐treatment caused g