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Adenovirus infection induces microglial activation: involvement of mitogen-activated protein kinase pathways

โœ Scribed by Narayan R Bhat; Fan Fan


Book ID
113998275
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
702 KB
Volume
948
Category
Article
ISSN
0006-8993

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Multiple studies demonstrate that manganese (Mn) exposure potentiates inflammatory mediator output from activated glia; this increased output is associated with enhanced mitogen activated protein kinase (MAPK: p38, ERK and JNK) activity. We hypothesized that Mn activates MAPK by activating the kinas