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An intramolecular carbocyclic [3 + 2] cycloaddition via organopalladium intermediates

โœ Scribed by Trost, Barry M.; Chan, Dominic M. T.


Book ID
118041655
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
377 KB
Volume
104
Category
Article
ISSN
0002-7863

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An intramolecular cycloaddition approach
โœ Yong He; Hossen Mahmud; Brian R Wayland; H.V.Rasika Dias; Carl J Lovely ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 86 KB

An approach to pyrrolo[3,2-c]quinolones is described which relies on an intramolecular azomethine ylide alkene cycloaddition reaction. Critical to the success of this reaction was the requirement for alkylation of the aniline nitrogen, in the absence of this substituent a decarboxylative-Michael add