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An international validation study of a Bhas 42 cell transformation assay for the prediction of chemical carcinogenicity

✍ Scribed by Ayako Sakai; Kiyoshi Sasaki; Kumiko Hayashi; Dai Muramatsu; Shoko Arai; Nobuko Endou; Sachiko Kuroda; Albrecht Poth; Susanne Bohnenberger; Thorsten Kunkelmann; Masumi Asakura; Hideki Hirose; Nana Ishii; Fukutaro Mizuhashi; Sawako Kasamoto; Miho Nagai; Kamala Pant; Shannon W. Bruce; Jamie E. Sly; Shojiro Yamazaki; Makoto Umeda; Noriho Tanaka

Book ID
116759966
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
977 KB
Volume
725
Category
Article
ISSN
1383-5718

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## Abstract __In vitro__ carcinogenesis assays, in mammalian cells, are proving to be a necessary part of batteries of __in vitro__ tests for detecting potential mutagens/carcinogens. The selection of which particular test to use requires an evaluation of test reliability, repeatability, sensitivit