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BALB/c 3T3 cell transformation assay for the prediction of carcinogenic potential of chemicals and environmental mixtures

✍ Scribed by Maria Grazia Mascolo; Stefania Perdichizzi; Francesca Rotondo; Elena Morandi; Angela Guerrini; Paola Silingardi; Monica Vaccari; Sandro Grilli; Annamaria Colacci

Book ID
116920235
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
324 KB
Volume
24
Category
Article
ISSN
0887-2333

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## Abstract A31–714, a subclone isolated from clone A31 of the BALB/3T3 line showed a high degree of contact inhibition and an extremely low incidence of spontaneous transformation. Treatment of this subclone with 4‐nitroquinoline‐1‐oxide, 3‐methylcholanthrene, benzo(a)pyrene or N‐methyl‐N'‐nitro‐N