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An Improved Synthesis of γ-(3,4-Ureylene-cyclohexyl)-butyric Acid

✍ Scribed by English, J. P.; Clapp, R. C.; Cole, Q. P.; Krapcho, J.


Book ID
127343958
Publisher
American Chemical Society
Year
1945
Tongue
English
Weight
397 KB
Volume
67
Category
Article
ISSN
0002-7863

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Synthesis of γ-amino[4-11C]butyric acid
✍ Gunnar Antoni; Bengt Långström 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 280 KB

A one-pot s nthesis of no-carrier added y-amin0[4-~~C]butyric acid (GABA) starting with h drogen [zC]cyanide prepared from [llC]carbon dioxide, is presented. Hydrogen [&]cyanide was trapped in tetrahydrofuradpotassium hydroxide in the presence of the amino polyether Kryptofix 2.2.2. A Michael additi