Synthesis and antitumor properties of 3(4)-chloro-4(3)-(2-chloroethylthio)butyric acid derivatives
β Scribed by L. Rasteikiene; A. Vektariene
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 173 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0091-150X
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π SIMILAR VOLUMES
The synthesis of the title compound is described. It involves base catalyzed substitution of deuterium for hydrogen in 3-p- -chlorophenylglutaric acid which is subsequently transformed to baclofen. The overall yield is 80%. ## INTRODUCTION AND DISCUSSION In order to develop a mass fragmentographi
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## Abstract Two preparations of carbonβ14 labelled 4βaminoβ3β(4βchlorophenyl)βbutyric acid are described : First, the label is introduced in the 3βposition of the butyric acid chain in nine steps, starting from ^14^CO~2~. The total radiochemical yield is 30%, calculated from the first labelled inte