An Improved Synthesis of 5′-Fluoro-5′-deoxyadenosines
✍ Scribed by Trent D. Ashton; Peter J. Scammells
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 20 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
I?. L. C a r g i l l . The generous g i f t s o f CF3OF f r o m Drs. W. B. Fox and R. A. Detllarco ( O f f i c e o f Naval Research, Washington) and seedcrystals o f D-arabinolactone from D r . H.
## Abstract A high yielding synthesis of 5,5‐dideuterocyclophosphamide is described which involves the base catalysed deuterium exchange of 3‐hydroxypropionitrile and subsequent medium pressure catalytic hydrogenation to yield 1‐amino‐2,2‐dideuteropropan‐3‐ol. This compound is condensed with N,N‐bi
## Abstract The synthesis of the title compound **2** is described. __N__‐Alkylation of 5′‐amino‐5′‐deoxy‐2′,3′‐__O__‐(1‐methylethylidene)adenosine (**3**) with [(3‐iodopropoxy)methyl]benzene gave after debenzylation the 5′‐deoxyadenosine derivative **4b**. After derivatization of the 5′‐NH, the te
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v