An improved preparation of 5′-deoxyadenosine by coupling methods
✍ Scribed by Leon M. Lerner
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 278 KB
- Volume
- 184
- Category
- Article
- ISSN
- 0008-6215
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The title method affords the title compound (V) in high purity and is suitable for scale‐up.
Pyridoxal Y-phosphate was synthesized by first oxidizing [Wlpyridoxine to [Wlpyridoxal with MnOp ["C]Pyridoxal, isolated by cation-exchange chromatography, was then reacted with ATP in the presence of rat liver pyridoxal kinase to form ["C]pyridoxal Y-phosphate. The rat liver enzyme was used instead
A safe procedure for the conversion of barium carbonate-I4C to potassium cyanide-I4C on a 6-7 mmol scale in 90-98% yield was developed. Barium carbonate-14C was heated with excess potassium azide in a matrix of sand without added potassium metal, allowing safe, rapid and convenient recovery of the c