An improved synthesis of [15N] 16-doxyl stearic acid

✍ Scribed by Joy Joseph; Ching-San Lai

• Book ID: 102375705
• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: French
• Weight: 264 KB
• Volume: 24
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580241003

✦ Synopsis

An improved method f o r t h e synthesis o f p N 1 16-Doxy1 stearate, a f a t t y -a c i d s p i n l a b e l , i s reported. The method r e q u i r e s o n l y one mole o f r15N] 2-anino-2-methyl propanol per mole o f methyl keto s t e a r a t e w i t h an o v e r a l l y i e l d o f about 50%. y i e l d . The q r e a t improvement i n y i e l d was achieved m a i n l y throuqh t h e r e d u c t i o n o f r e a c t i o n volume which increases t h e r e a c t i o n r a t e b y t h e law o f mass action.