𝔖 Bobbio Scriptorium
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An improved synthesis of 1-aminophosphonic acids

✍ Scribed by Jozef Oleksyszyn; Roman Tyka


Book ID
104235384
Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
57 KB
Volume
18
Category
Article
ISSN
0040-4039

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Syntheses of α-Aminophosphonic Acids, VI
✍ Groth, Ulrich ;Lehmann, Lutz ;Richter, Lutz ;Schöllkopfh, Ulrich 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 580 KB

## Abstract The lithium or potassium derivative of diethyl isocyanomethylphosphonate (1) reacts with epoxides in the presence of boron trifluoride–diethyl ether to provide the diethyl 3‐hydroxy‐1‐isocyanoalkylphosphonates __rac__‐3. The corresponding mesylates __rac__‐4 undergo a base‐mediated cycl