𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Asymmetric synthesis ofα-aminophosphonic acids

✍ Scribed by A. Alami; F. Ouazzani; M. -L. Roumestant; Ph. Viallefont; A. el Hallaoui

Book ID
104949655
Publisher
Springer
Year
1992
Tongue
English
Weight
102 KB
Volume
2
Category
Article
ISSN
0939-4451

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Asymmetric Synthesis of α-Aminophosphoni
Asymmetric Synthesis of α-Aminophosphonic Acids by Cycloaddition of N-Glycosyl-C-dialkoxyphosphonoylnitrones
✍ Andrea Vaseila; Robert Voeffray 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 German ⚖ 823 KB

## Abstract Addition of dialkyl phosphites to the nitrone **6**, formed __in situ__ from the oxime **5** and formaldehyde gave the hydroxylamines **7** (86%) and **8** (88%), which reacted with __p__‐benzoquinone in the presence of ethylene __via__ the __C__‐dialkoxyphosphonoylnitrones **9** and **

Asymmetric synthesis of α-aminophosphoni
Asymmetric synthesis of α-aminophosphonic acids, I enantioselective synthesis of L-(1-aminoethyl)phosphonic acid by asymmetric catalytic hydrogenation ofN-[1-(dimethoxyphosphoryl)ethenyl]formamide
✍ Schöllkopf, Ulrich ;Hoppe, Inga ;Thiele, Angelika 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 275 KB

## Abstract The synthesis of __N__‐[bis(dimethoxyphosphoryl)methyl]formamide (**7**) from aminomethylene‐bis(phosphonic acid) (**6**) is described. **7** reacts with aldehydes in a Wittig‐Horner reaction to give __N__‐[1‐(dimethoxyphosphoryl)‐1‐alkenyl]formamides **3**. From the parent compound **3

A new efficient procedure for asymmetric
A new efficient procedure for asymmetric synthesis of α-aminophosphonic acids via addition of lithiated bis(diethylamino)phosphine borane complex to enantiopure sulfinimines
✍ Marian Mikołajczyk; Piotr Łyżwa; Józef Drabowicz 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 193 KB

The addition of lithiated bis(diethylamino)phosphine borane complex to enantiopure p-toluenesulfinimines is highly diastereoselective, affording the corresponding addition products with high efficiency (yields from 72 to 100%). The addition products were readily converted into a-amino-a-arylmethylph

Asymmetric Mannich-Type Synthesis of N-P
Asymmetric Mannich-Type Synthesis of N-Phosphinyl α-Aminophosphonic Acid Monoesters
✍ Zhijia Fang; Haohao Yang; Zhiwei Miao; Ruyu Chen 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 German ⚖ 198 KB

## Abstract A convenient diastereoselective synthesis of diisopropyl (2__R__,3__R__)‐3‐{{{(__R__/__S__)‐aryl[(diethoxyphosphinyl)amino]methyl}hydroxyphosphinyl}oxy}‐2‐hydroxybutanedioate through __Mannich__‐type reactions is reported. The reactions take place under mild conditions in good yields, a

Asymmetric Syntheses of α-Aminophosphoni
Asymmetric Syntheses of α-Aminophosphonic Acids, V. Synthesis of Enantiomerically Pure Diethyl 2-Pyrrolidinyl- and 5-Oxo-2-pyrrolidinylphosphonates
✍ Groth, Ulrich ;Richter, Lutz ;Schöllkopf, Ulrich 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 791 KB

## Abstract Enantiomerically pure 3‐ and 4‐substituted phosphonic acid derivatives 5 of pyroglutamic acid were prepared by a Michael addition of the lithiated (+)‐camphor derivative 2 to α,β‐unsaturated esters and subsequent hydrolysis. The reduction of the lactams 5 with LiBH~4~/BF~3~ · OEt~2~ aff