## Abstract Enantiomerically pure 3‐ and 4‐substituted phosphonic acid derivatives 5 of pyroglutamic acid were prepared by a Michael addition of the lithiated (+)‐camphor derivative 2 to α,β‐unsaturated esters and subsequent hydrolysis. The reduction of the lactams 5 with LiBH~4~/BF~3~ · OEt~2~ aff
✦ LIBER ✦
SYNTHESIS OF ENANTIOMERICALLY PURE AMINOPHOSPHONIC ACIDS
✍ Scribed by Jacquier, Robert; Ouazzani, Fouad; Roumestant, Marie-louise; Viallefont, Philippe
- Book ID
- 120802257
- Publisher
- Informa UK (Taylor & Francis)
- Year
- 1988
- Weight
- 268 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0308-664X
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