𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An Improved Procedure for N- to C-Directed (Inverse) Solid-Phase Peptide Synthesis

✍ Scribed by Johansson, Anja; Åkerblom, Eva; Ersmark, Karolina; Lindeberg, Gunnar; Hallberg, Anders

Book ID
120386777
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
143 KB
Volume
2
Category
Article
ISSN
1520-4766

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Investigations on Solid-Phase Peptide Sy
Investigations on Solid-Phase Peptide Synthesis in N-to-C Direction (Inverse Synthesis)
✍ Henkel, Bernd ;Zhang, Lianshan ;Bayer, Ernst 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 757 KB

## Abstract The possibility of peptide assembly in the N‐C direction by using HOBt salts of the amino acid 9‐fluorenylmethyl esters has been investigated. The first amino acid derivative has to be coupled with the N‐terminus to the polymer‐bound trityl linker. Determination of the loading with the

An improved deblocking agent for direct
An improved deblocking agent for direct Fmoc solid-phase synthesis of peptide thioesters
✍ Xianzhang Bu; Guiyang Xie; Chi Wang Law; Zhihong Guo 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 133 KB

To synthesize peptide thioesters directly on a solid support for use as substrate analogues for thioesterases in non-ribosomal peptide synthases, we modified a reagent compatible with Fmoc solid-phase peptide synthesis that efficiently removes the protecting group while keeping the thioester intact.