An improved method for the synthesis of cylamino acids through 2,4-disubstituted 2-imidazolin-5-ones.
✍ Scribed by Ganapathiplackal M. Devasia; C.Rajasekharan Pillai
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 113 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
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## Abstract An improved synthesis for the preparation of 3‐oxo‐1,2,5‐thiadiazolidine 1,1‐dioxides has been developed. This facile two‐step procedure fromα‐amino acid esters and chlorosulfonyl isocyanate results in excellent yields of products.
## Abstract A number of symmetrical 3,5‐disubstituted‐4__H__‐1,2,4‐triazoles have been synthesized in good yields by deamination of the corresponding 4‐amino‐1,2,4‐triazoles __via__ reductive diazotation of these amino compounds in the presence of hypophosphorous acid. Analytical, spectral data and