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An Efficient Process for the Synthesis of trans-2,3-Disubstituted-2,3-dihydro-4H-1-benzopyran-4-ones (Chroman-4-ones)

✍ Scribed by Richard W. Draper; Bin Hu; Radha V. Iyer; Xun Li; Yuelie Lu; Mohammad Rahman; Eugene J. Vater


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
158 KB
Volume
56
Category
Article
ISSN
0040-4020

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Efficient synthesis of 4,4-disubstituted
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A simple method for the preparation of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2dioxides is described. Treatment of N-sulfonyl ketimines 2 and 3 with different carbon nucleophiles afforded the corresponding of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides 1 i