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An improved procedure for the deamination of symmetrical 3,5-disubstituted 4-amino-1,2,4-triazoles

✍ Scribed by Fouad Bentiss; Michel Lagrenee; Hervéa Vezin; Marya Bouanis; Bouchaib Mernari

Publisher
Journal of Heterocyclic Chemistry
Year
2002
Tongue
English
Weight
51 KB
Volume
39
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

A number of symmetrical 3,5‐disubstituted‐4__H__‐1,2,4‐triazoles have been synthesized in good yields by deamination of the corresponding 4‐amino‐1,2,4‐triazoles via reductive diazotation of these amino compounds in the presence of hypophosphorous acid. Analytical, spectral data and theoretical calculations confirmed the structures of the new triazole derivatives.

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