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An improved hapten design for the radioimmunoassay of steroid glucuronides

✍ Scribed by Rukhsana Chaudhri; W.F. Coulson


Book ID
116001879
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
542 KB
Volume
13
Category
Article
ISSN
0022-4731

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✍ Nariman B. Mehta; David L. Musso πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 302 KB πŸ‘ 1 views

The synthesis of a hapten useful in the radioimmunoassay of bupropion is described. Since bupropion has no functional group that can be easily derivatized, a hydroxypropyl group was incorporated into the molecule. Studies in cross-reactivity with possible metabolites required the synthesis of the 4'