Design and synthesis of a hapten for the
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Nariman B. Mehta; David L. Musso
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Article
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1986
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John Wiley and Sons
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English
β 302 KB
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The synthesis of a hapten useful in the radioimmunoassay of bupropion is described. Since bupropion has no functional group that can be easily derivatized, a hydroxypropyl group was incorporated into the molecule. Studies in cross-reactivity with possible metabolites required the synthesis of the 4'