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Hapten-radioimmunoassay: A general procedure for the estimation of steroidal and other haptenic substances

✍ Scribed by A.Rees Midgley Jr.; G.D. Niswender; J.Sri Ram


Book ID
118977599
Publisher
Elsevier Science
Year
1969
Tongue
English
Weight
387 KB
Volume
13
Category
Article
ISSN
0039-128X

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The synthesis of a hapten useful in the radioimmunoassay of bupropion is described. Since bupropion has no functional group that can be easily derivatized, a hydroxypropyl group was incorporated into the molecule. Studies in cross-reactivity with possible metabolites required the synthesis of the 4'