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An IMDA approach to tigliane and daphnane diterpenoids: Generation of the tetracyclic ring system of the tiglianes

โœ Scribed by Philip C Bulman Page; David C Jennens; Heather McFarland

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
253 KB
Volume
38
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A synthesis of the tetracyclic ring system of phorbol and other tigliane diterpenes has been achieved in six steps using an unusual intrarnolecular Diels-Alder reaction both as the key stereocontrolling process and to introduce a double bond appropriately positioned for functionalization as a cyclopropane.

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