ChemInform Abstract: An IMDA Approach to Tigliane and Daphnane Diterpenoids: Generation of the Tetracyclic Ring System of the Tiglianes.

✍ Scribed by P. C. B. PAGE; D. C. JENNENS; H. MCFARLAND

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 28 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199752201

✦ Synopsis

An IMDA Approach to Tigliane and Daphnane Diterpenoids: Generation of the Tetracyclic Ring System of the Tiglianes.

-The tetracyclic compound (V) representing the ring system of phorbol and other tigliane diterpenes is prepared using an unusual intramolecular Diels-Alder reaction of (I) followed by a cyclopropanation of the mixture (II) and (III).