An extended tTDT test for uncertain haplotype transmission
โ Scribed by D. CLAYTON
- Book ID
- 111111232
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 260 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0003-4800
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## Abstract The present study introduces new Haplotype Sharing Transmission/Disequilibrium Tests (HSโTDTs) that allow for random genotyping errors. We evaluate the type I error rate and power of the new proposed tests under a variety of scenarios and perform a power comparison among the proposed te
Two tests for allelic association were applied to a simulated complex disease for the Genetic Analysis Workshop 9. The transmission/disequilibrium test [Spielman et al., 19931 and the haplotype-based haplotype relative risk approach [Terwilliger and Ott, 19921 were used to detect disease-associated