Transmission/Disequilibrium Tests for Extended Marker Haplotypes
β Scribed by David Clayton; Hywel Jones
- Book ID
- 117852989
- Publisher
- American Society of Human Genetics
- Year
- 1999
- Tongue
- English
- Weight
- 138 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/302566
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Association tests of multilocus haplotypes are of interest both in linkage disequilibrium mapping and in candidate gene studies. For caseβparent trios, I discuss the extension of existing multilocus methods to include ambiguous haplotypes in tests of models which distinguish between the
## Abstract The present study introduces new Haplotype Sharing Transmission/Disequilibrium Tests (HSβTDTs) that allow for random genotyping errors. We evaluate the type I error rate and power of the new proposed tests under a variety of scenarios and perform a power comparison among the proposed te