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An expeditious synthesis of (3S,4S)-statine and (3S,4S)cyclohexylstatine

✍ Scribed by Yoshiji Takemoto; Teruyo Matsumoto; Yoshio Ito; Shiro Terashima

Book ID
104226485
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
183 KB
Volume
31
Category
Article
ISSN
0040-4039

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✦ Synopsis

The title synthesis could be accomplished by employing highly stereoselective aldol reaction of Omethyl-0-trimethylsilyl ketene acetal with the (S)-a-amido aldehyde (2) in the presence of titanium (IV) chloride as a key step.

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