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An expeditious synthesis of a (3S,4S,5R)-trihydroxyazepane

โœ Scribed by Dilip D. Dhavale; Vinod D. Chaudhari; Jayant N. Tilekar

Book ID
104254408
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
101 KB
Volume
44
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A practical approach for the synthesis of the (2S,3S,4R)-trihydroxyazepane 1d has been reported. Starting from a-D-xylo-pentodialdose, readily available from D-glucose, the sequence involves Wittig olefination and reductive amination as key steps.

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