An exception of eschweiler-clarke methyl
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Fu-Lin Chen; Kuangsen Sung
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Article
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2004
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Journal of Heterocyclic Chemistry
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English
⚖ 172 KB
## Abstract An exception of Eschweiler‐Clarke methylation was found for α‐amino amides. The α‐amino amides on treatment with formaldehyde and formic acid produce cyclocondensation products, imidazolidin‐4‐ones, but __N__‐methylation process becomes important when three substituents of the α‐amino a