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An Efficient Synthesis of the Cholinergic Channel Activator ABT-418

✍ Scribed by Wittenberger, Steven J.

Book ID
118247719
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
136 KB
Volume
61
Category
Article
ISSN
0022-3263

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ABT-418[(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole] is a novel cholinergic channel activator (ChCA) and, like the prototypic ChCA (-)-nicotine, has cognition enhancing and anxiolytic effects. It appears, however, to have fewer central nervous system (CNS) or peripheral side effects compared t

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