Effects of the cholinergic channel activ
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Richard J. Radek; Clark A. Briggs; James P. Sullivan; Chae-Hee Kang; Stephen P.
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Article
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1996
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John Wiley and Sons
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English
⚖ 683 KB
ABT-418[(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole] is a novel cholinergic channel activator (ChCA) and, like the prototypic ChCA (-)-nicotine, has cognition enhancing and anxiolytic effects. It appears, however, to have fewer central nervous system (CNS) or peripheral side effects compared t