An efficient synthesis of the basic pyrrolidine ring for the kainoids
β Scribed by Sung-Eun Yoo; Sang-Hee Lee; Nak-Jung Kim
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 123 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
An improved synthesis of the 5-Oxo-hexahydro-pyrrolo[3,2-b]pyrrole ring system (Pyrrolidine-5,5trans-lactam ring system) has been achieved using cyclisation of the amino ethyl ester 4 with t-butyl magnesium chloride in THF to give the translactam 5 in 78% yield
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