๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

An efficient synthesis of optically active 4-demethoxy anthracyclinones

โœ Scribed by Fatima Bennani; Jean-Claude Florent; Michel Koch; Claude Monneret

Book ID
108372676
Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
874 KB
Volume
40
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Anthracyclinones VI. Diastereoselective
Anthracyclinones VI. Diastereoselective synthesis of 7,10-dihydroxy-4-demethoxy-anthracyclinones
โœ Emmanuel Bertounesque; Jean-Claude Florent; Claude Monneret ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 289 KB

The total synthesis of two new enantiomerically pure anthracyclinones 9 and 10 from leucoquinizarin 2 and chiral aldehyde 3 readily obtained from a-D-isosaccharinolactone. is described. The stereochemical results are discussed. We have previously reported 2 an efficient synthesis of 1 from leucoqui

Asymmetric synthesis of optically active
Asymmetric synthesis of optically active anthracyclinones
โœ Shiro Terashima; Sang-sup Jew; Kenji Koga ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 296 KB

The anthracycline antibiotics adriamycin(3 and daunorubicin(8 are of current interest because of their activity against various experimental tumors as well as certain types of human cancer.') Studies on the structure-activity relationship have revealed that 4-demethoxy analogues of !, and g show imp