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An Efficient Synthesis of N -Substituted-3-aryl-3-(4-hydroxy-6-methyl-2-oxo-2 H -pyran-3-yl)propanamides by Four-Component Reaction in Aqueous Medium

✍ Scribed by Dou, Guo-Lan; Wang, De-Ming; Zhong, Xiao-Xing; Shi, Da-Qing


Book ID
121272643
Publisher
Journal of Heterocyclic Chemistry
Year
2013
Tongue
English
Weight
431 KB
Volume
50
Category
Article
ISSN
0022-152X

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## Abstract A mild and efficient synthesis of __N__‐substituted‐3‐aryl‐3‐(2‐hydroxy‐4,4‐dimethyl‐6‐oxocyclohex‐1‐enyl)propanamides via four‐component reaction of an aldehyde, amine, Meldrum's acid and 5,5‐dimethylcyclo‐hexane‐1,3‐dione in the presence of benzyltriethylammonium chloride (TEBAC) in a