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ChemInform Abstract: An Efficient Synthesis of N-Substituted-3-aryl-3- (2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)propanamides by Four-Component Reaction in Aqueous Medium.

✍ Scribed by Guolan Dou; Xiaoxing Zhong; Deming Wang; Daqing Shi


Publisher
John Wiley and Sons
Year
2012
Weight
25 KB
Volume
43
Category
Article
ISSN
0931-7597

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An Efficient Synthesis of N-Substituted-
✍ Guolan Dou; Xiaoxing Zhong; Deming Wang; Daqing Shi 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB

## Abstract A mild and efficient synthesis of __N__‐substituted‐3‐aryl‐3‐(2‐hydroxy‐4,4‐dimethyl‐6‐oxocyclohex‐1‐enyl)propanamides via four‐component reaction of an aldehyde, amine, Meldrum's acid and 5,5‐dimethylcyclo‐hexane‐1,3‐dione in the presence of benzyltriethylammonium chloride (TEBAC) in a