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An Efficient Synthesis of 4-(Phenylsulfonyl)-4 H -furo[3,4- b ]indoles

โœ Scribed by Gribble, Gordon W.; Jiang, Jun; Liu, Yanbing


Book ID
126201707
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
41 KB
Volume
67
Category
Article
ISSN
0022-3263

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๐Ÿ“œ SIMILAR VOLUMES


4-(phenylsulfonyl)-4H-furo[3,4-b]indole
โœ Mark G. Saulnier; Gordon W. Gribble ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 237 KB

The N-phenylsulfonyl derivative (2) of the previously unknown fused heterocycle 4Hfuro[3,4-blindole is synthesized from indole-3-carboxaldehyde (2) in 28% yield and undergoes a Diels-Alder reaction with benzyne to give 5H-benzo[b]carbazole (11) in -33% yield after deoxygenation and deprotection.

2-(4-Methoxybenzyl)-4-(phenylsulfonyl)-1
โœ Kishbaugh, Tara L. S. ;Gribble, Gordon W. ;Jasinski, Jerry P. ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› International Union of Crystallography ๐ŸŒ English โš– 735 KB

The indole and pyrrolidine ring systems of the title compound, C 24 H 22 N 2 O 3 S, are essentially coplanar. The angle between the planes of the phenylsulfonyl group and the indole ring system is 89.1 (2) , which is characteristic of 1-(phenylsulfonyl)indoles. The benzyl ring is nearly perpendicula