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An efficient synthesis of 3-acylcarbazoles and observations on the further elaboration of these compounds to 6h-pyridocarbazoles

✍ Scribed by Iain Hogan; Paul Jenkins; Malcolm Sainsbury

Book ID: 104217827
Publisher: Elsevier Science
Year: 1988
Tongue: French
Weight: 243 KB
Volume: 29
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)82385-0

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✦ Synopsis

A new procedure for the synthesis of 3-acylcarbazoles useful for the construction of 6H-pyrido[4,3-b]carbazoles is described starting from readily available gramines, or indoles. This methodology is exemplified by a synthesis of the anticancer alkaloid olivacine. Some discrepancies are noted between our results and those of other authors.

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