An efficient synthesis of 2,4-dideoxy-4-hydroxyphosphinyl-d-erythro-pentofuranose
โ Scribed by Tadashi Hanaya; Ayashi Noguchi; Hiroshi Yamamoto
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 224 KB
- Volume
- 209
- Category
- Article
- ISSN
- 0008-6215
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๐ SIMILAR VOLUMES
The preparation of the previously undescribed class of 4-deoxy-and 2,4-dideoxy-2-acetamido-b-D-threo-hex-3-enopyranosides was accomplished with a very high yield and a complete regioselectivity by means of a simultaneous activation-elimination process of the OH-4 group of b-D-talopyranosides (5a,b)
4,6-Di-O-acetyl-2,3-dideoxy-D-erythro-hex-2-enopyranose (4,6-di-o-acetyl-D-pseudoglucal), prepared from 3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-arubinohex-1-enitol (tri-0-acetyl-D-glucal), was condensed, by catalysis with boron trifluoride, with an equivalent of the original glycal, to give crystal