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An efficient route to 3-aminoindazoles and 3-amino-7-azaindazoles

✍ Scribed by Michael J. Burke; Brian M. Trantow

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
177 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

A non-acidic procedure for the preparation of 3-aminoindazoles and 3-amino-7-azaindazoles from 2-fluoroaryl carboxylic acids is reported. The synthesis starts from readily available starting materials and uses mild and practical reaction conditions in a three-step overall procedure. Products were isolated for a number of examples, but yields varied significantly depending on electronic nature of the substituents.

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