An efficient protocol for a sharpless style racemic dihydroxylation
β Scribed by Jason Eames; Helen J. Mitchell; Adam Nelson; Peter O'Brien; Stuart Warren; Paul Wyatt
- Book ID
- 103401234
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 235 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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Dihydroxylation of ene ester systems was achieved in good yield and diastereoselectivity under classical catalytic OsO( and NMO conditions using the intrinsic diastereoselectivity in a-methyl ~-OTBS systems. This inlxinsic diastereoselection can be reversed using 'super' AD-mix to give the opposite
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