## Abstract A series of 3‐methyl‐1,4‐disubstituted‐4,5‐dihydro‐1__H__‐pyrazolo[3,4‐__b__]pyridine‐6(7__H__)‐ones was synthesized __via__ the three‐component reaction of aldehyde, 3‐methyl‐1‐phenyl‐1__H__‐pyrazol‐5‐amine, and Meldrum's acid catalyzed by L‐proline. This protocol has the advantages of
An efficient one-pot three-component synthesis of tetrahydrofuro[3,4-b]quinoline-1,8(3H,4H)-dione derivatives catalyzed by L-proline
✍ Scribed by Chun-Ling Shi; Hui Chen; Daqing Shi
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 85 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.782
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✦ Synopsis
Abstract
L‐Proline is found to be an efficient catalyst for the synthesis of tetrahydrofuro[3,4‐b]quinoline‐1,8(3__H__,4__H__)‐dione derivatives. This protocol is novel and has the advantages of mild condition, high yield, and easy operation. J. Heterocyclic Chem., (2012).
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## Abstract magnified image An efficient method for the synthesis of a series of 4‐phenylhexahydro‐__1H__‐pyrano[2,3‐__d__]pyrimidin‐2(8a__H__)‐one derivatives via the one‐pot three‐component reaction of aromatic aldehydes, urea or thiourea and 3,4‐dihydro‐2__H__‐pyran in DMF/CH~3~CN using __p__‐T
## Abstract A series of 4‐aryl‐3,7,7‐trimethyl‐1‐phenyl‐7,8‐dihydro‐1__H__‐pyrazolo[3,4‐__b__]quinolin‐ 5(6__H__)‐ones were synthesized by the three‐component reaction of aromatic aldehydes, 3‐methyl‐1‐phenyl‐1__H__‐pyrazol‐5‐amine, and 5,5‐dimethyl‐1,3‐cyclohexandione in the presence of sodium 1‐d