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An efficient one-pot synthesis of tri-substituted thiophenes via a multicomponent reaction in water

✍ Scribed by Moghaddam, Firouz Matloubi; Bardajee, Ghasem Rezanejade; Dolabi, Maliheh


Book ID
120590358
Publisher
Taylor and Francis Group
Year
2010
Tongue
English
Weight
465 KB
Volume
31
Category
Article
ISSN
1741-5993

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## Abstract An efficient environmentally friendly synthesis of poly‐substituted pyrimidines has been developed via a four‐component, one‐pot reaction of malononitrile, carbon disulfide, alkyl halide and __S__‐alkylisothiouronium salt in water at room temperature. Water as solvent, mild reaction con