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A Facile One-Pot Synthesis of Substituted Quinolines via New Multicomponent Reaction

✍ Scribed by Amir Rineh; Mohammad A. Khalilzadeh; Mohammad M. Hashemi; Medí Rajabi; Fatemeh Karimi

Book ID
115558826
Publisher
Journal of Heterocyclic Chemistry
Year
2012
Tongue
English
Weight
295 KB
Volume
49
Category
Article
ISSN
0022-152X

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A Novel One-Pot Synthesis of Substituted
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## Abstract A synthesis of quinoline derivatives is described __via__ reaction between ethyl bromopyruvate (=ethyl 3‐bromo‐2‐oxopropanoate), acetylenedicarboxylate, and isatin (=1__H__‐indole‐2,3‐dione) in the presence of NaH as a base. Also, these reactions were performed without ethyl bromopyruva

ChemInform Abstract: Heterocyclizations
ChemInform Abstract: Heterocyclizations via TosMIC-Based Multicomponent Reactions: A New Approach to One-Pot Facile Synthesis of Substituted Quinoxaline Derivatives.
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