✦ LIBER ✦

A Novel One-Pot Synthesis of Substituted Quinolines

✍ Scribed by Maryam Sabbaghan; Issa Yavari; Zinatossadat Hossaini; Sanaz Souri

Publisher: John Wiley and Sons
Year: 2010
Tongue: German
Weight: 134 KB
Volume: 93
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200900304

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A synthesis of quinoline derivatives is described via reaction between ethyl bromopyruvate (=ethyl 3‐bromo‐2‐oxopropanoate), acetylenedicarboxylate, and isatin (=1__H__‐indole‐2,3‐dione) in the presence of NaH as a base. Also, these reactions were performed without ethyl bromopyruvate. The reaction in the presence of ethyl bromopyruvate provides regioselectively a quinoline with the ethyl ester group in 4‐position. In the absence of ethyl bromopyruvate, the reaction leads to functionalized quinolines with the same ester groups in 2‐, 3‐, and 4‐positions.

📜 SIMILAR VOLUMES

ChemInform Abstract: A Novel One-Pot Syn

ChemInform Abstract: A Novel One-Pot Synthesis of Substituted Quinolines.

✍ Maryam Sabbaghan; Issa Yavari; Zinatossadat Hossaini; Sanaz Souri 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 24 KB 👁 2 views

ChemInform Abstract: A Domino Three-Comp

ChemInform Abstract: A Domino Three-Component Condensation of ortho-Haloacetophenones with Urea or Amines: A Novel One-Pot Synthesis of Halogen-Substituted Quinolines.

✍ Chuanmei Qi; Qingwei Zheng; Ruimao Hua 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

ChemInform Abstract: Copper-Catalyzed On

ChemInform Abstract: Copper-Catalyzed One-Pot Synthesis of Substituted Benzimidazo[1,2-a]quinolines.

✍ Bing-Wei Zhou; Jian-Rong Gao; Dong Jiang; Jian-Hong Jia; Zhen-Ping Yang; Hong-We 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

A Facile One-Pot Synthesis of Novel Subs

A Facile One-Pot Synthesis of Novel Substituted 1,2,3,4-Tetrahydropyrimidines.

✍ Enamul Karim; Kaushal Kishore; Jai N. Vishwakarma 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 94 KB 👁 1 views

A facile one-pot synthesis of novel subs

A facile one-pot synthesis of novel substituted 1,2,3,4-tetrahydropyrimidines

✍ Enamul Karim; Kaushal Kishore; Jai N. Vishwakarma 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 28 KB 👁 1 views

## Abstract A facile one‐pot synthesis of 5‐benzoyl‐6‐methylthio‐1,2,3,4‐tetrahydropyrimidines in good yields is reported.

Molecular Iodine Catalyzed One-Pot Synth

Molecular Iodine Catalyzed One-Pot Synthesis of Substituted Quinolines from Imines and Aldehydes.

✍ Xu-Feng Lin; Sun-Liang Cui; Yan-Guang Wang 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 21 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.