An Efficient Diastereoselective Route to Differentially Protected anti -4-Amino-1-alken-3-ols
β Scribed by Lombardo, Marco; Mosconi, Elisa; Pasi, Filippo; Petrini, Marino; Trombini, Claudio
- Book ID
- 120604722
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 75 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
A simple method to introduce an heteroatom substituent at C-5 of isothiazole dioxides is reported. Through Michael addition reaction 5-substituted isothiazole and 4,5-dihydroisothiazole 1,1-dioxides were obtained allowing the preparation of a series of derivatives of special interest for biological
Isothiazoles. Part 9. An Efficient Synthetic Route to 5-Substituted-3-amino-4-arylisothiazole 1,1-Dioxides and Their 4,5-Dihydro Derivatives. -The thiazole dioxide (I) does not react with alcohols, while the derivative (VIII) does not undergo addition with aliphatic and aromatic amines but with the
## Abstract By a oneβpot tandem __Ugi__ multicomponent reaction (MCR)/click reaction sequence not requiring protecting groups, 1__H__β1,2,3βtriazoleβmodified __Ugi__βreaction products **6a**β**6n** (__Schemeβ 1__ and __Tableβ 2__), **7a**β**7b** (__Tableβ 4__), and **8** (__Schemeβ 2__) were synthesize