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An efficient asymmetric synthesis of both enantiomers of phosphinothricin

โœ Scribed by Hans-Joachim Zeiss


Book ID
108382720
Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
165 KB
Volume
28
Category
Article
ISSN
0040-4039

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The asymmetric synthesis of both enantio
โœ Romano Di Fabio; Claudio Pietra; Russell J. Thomas; Luigi Ziviani ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 239 KB

The asymmetric synthesis of both enantiomers of the racemic NMDA antagonist eliprodil was accom lished in a novel application of Shsrpless' asymmetric diiydroxylation (AD) methodology. A drf erence in neuroprotective activity was noted for the enantiomers in an in viva \*P model of rat focal cerebra