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An automated version of the fluorescence-detected alkaline DNA-unwinding (FADU) assay to measure DNA strand breaks and DNA repair

✍ Scribed by M. Moreno-Villanueva; R. Pfeiffer; M. Müller; A. Leake; T. Kirkwood; T. Sindlinger; A. Bürkle

Book ID
113614839
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
45 KB
Volume
42
Category
Article
ISSN
0531-5565

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✍ María Moreno-Villanueva; Ragen Pfeiffer; Thilo Sindlinger; Alan Leake; Marcus Mü 📂 Article 📅 2009 🏛 BioMed Central 🌐 English ⚖ 419 KB

## Abstract ## Background Formation and repair of DNA single-strand breaks are important parameters in the assessment of DNA damage and repair occurring in live cells. The 'Fluorimetric Detection of Alkaline DNA Unwinding (FADU)' method [Birnboim HC, Jevcak JJ. Cancer Res (1981) 41:1889–1892] is a