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17. Quantification of DNA strand breaks by an automated version of fluorometric detection of alkaline unwinding (FADU)

✍ Scribed by M. Moreno-Villanueva; R. Steinhaus; T.A. Bürkle

Book ID: 113615182
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 41 KB
Volume: 44
Category: Article
ISSN: 0531-5565
DOI: 10.1016/j.exger.2008.08.031

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## Abstract ## Background Formation and repair of DNA single-strand breaks are important parameters in the assessment of DNA damage and repair occurring in live cells. The 'Fluorimetric Detection of Alkaline DNA Unwinding (FADU)' method [Birnboim HC, Jevcak JJ. Cancer Res (1981) 41:1889–1892] is a