An approach to the bakkanes. A short, stereocontrolled total synthesis of (.+-.)-bakkenolide A
β Scribed by Greene, Andrew E.; Depres, Jean Pierre; Coelho, Fernando; Brocksom, Timothy J.
- Book ID
- 127281718
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 448 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
A short synthesis of racemic homogynolide-B is described. The key step of the approach, cycloaddition of dichloroketene with the 2,2-dimethyltrimethylene acetal of 2,3-dimethyl-3-cyclohexen-l-one, proceeds with excellent selectivity and in high yield. The bakkanes, a relatively small group of hydri
Dheu-Andries for help with the molecular modeling studies, Mr. F. Bargiggia and Mr. M. Cook for some preliminary experiments, and Prof. M. Kawai (Nagoya Institute of Technology) for samples of natural bakkenolide B and bakkenolide III. Financial support from the Universite Γ Joseph Fourier and the C