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An approach to enantiomerically pure inverse γ-turn mimetics for use in solid-phase synthesis

✍ Scribed by Kay Brickmann; Peter Somfai; Jan Kihlberg


Book ID
104257054
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
255 KB
Volume
38
Category
Article
ISSN
0040-4039

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✍ K. BRICKMANN; P. SOMFAI; J. KIHLBERG 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB

An Approach to Enantiomerically Pure Inverse γ-Turn Mimetics for Use in Solid-Phase Synthesis. -The carboxyl group of the title mimetic (VII), which corresponds to a Phe-Ala-Ala synthon, may be linked to peptides. Reduction of the azido group renders possible elongation at the N-terminus thus allowi