An Antibody-Catalyzed Oxy-Cope Rearrangement
โ Scribed by Braisted, Andrew C.; Schultz, Peter G.
- Book ID
- 127199311
- Publisher
- American Chemical Society
- Year
- 1994
- Tongue
- English
- Weight
- 212 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## An aromatic oxy-Cope rearrangement can be achieved under anionic conditions (KH f HMPAl in Zow yield with a nuphthalene ring but not a phenyt. We have recently measured the activation parameters for an aromatic Cope rearrangement,l and these sug,oest that rearrangement of 4-phenyl-1-butene wou
Electrophile initiated acetylenic oxy Cope rearraqemmt of divmelysubstituted 5-Hcxen-1-yn-3-01s leads to the cwrespuWgaC6 -diethylmlc aldehydes or ketones In 9ood yields wlth mainly the E conf iguraticn fw both tile bonds. Silver nitrate and Silver triflwromethanesulfonate appear to be the most suit
Abstrack Two examples of the title maction = described. While the kinetically p&end pathway for 2 utilizes tlw vinyl substituent, that far 16 skirts this option cmnpletely. To a great extent, these biases are a function of the sauctud features inherent to these aicohoir. Although oxy-cope rearrange