An antibody-catalyzed bimolecular Diels-Alder reaction
โ Scribed by Braisted, Andrew C.; Schultz, Peter G.
- Book ID
- 126172083
- Publisher
- American Chemical Society
- Year
- 1990
- Tongue
- English
- Weight
- 295 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
The Diels-Alder cycloadditions of trans- and cis-piperylene (1 and 2) to 4-nitroso-N-propylbenzamide (3) were selected as target reactions for the development of catalytic antibodies with regioselective and enantioselective properties (Meekel, A. A. P. Ph.D. Thesis, University of Amsterdam, 1995). T
## Abstract A series of substituted thiophene dioxides was tested as diene substrates for the antibody 1E9, which was elicited with a hexachloronorbornene derivative and normally catalyzes the inverse electronโdemand __DielsโAlder__ reaction between 2,3,4,5โtetrachlorothiophene dioxide (TCTD) and _