First Example of an Antibody-Catalyzed Aza Diels—Alder Reaction.
✍ Scribed by Zhen-Dan Shi; Bing-Hui Yang; Yu-Lin Wu; Ya-Juan Pan; Yong-Yong Ji; Ming Yeh
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A series of substituted thiophene dioxides was tested as diene substrates for the antibody 1E9, which was elicited with a hexachloronorbornene derivative and normally catalyzes the inverse electron‐demand __Diels–Alder__ reaction between 2,3,4,5‐tetrachlorothiophene dioxide (TCTD) and _
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